Thanks to this thread on airliners.net I found some interesting model railway related "sights" in Prague. One suggested accommodation was the Ibis Hotel Mala Strana. Close by is Railroad Kingdom. My Googling also found the Vytopna Restaurant in Prague where the drinks are served by model trains.
Part of the Kamioka zinc mining and smelter complex Just after posting about the Kamioka Railway another photo from that 2006 set piqued my interest. Up there in the mountains the landscape looked blasted not just by winter but by something more. It was the kind of lonely place where you would not expect to find major industry, so this sight was quite surprising. Even more surprising is the history associated with this photo. According to some sources mining and refining of ores in Kamioka dates back to 710 AD and only closed in 2001. Undoubtedly the mine was a major reason for the existence of the Kamioka Railway. Refining of zinc still continues to this day under the parent Mitsui Kenzoku zaibatsu . Gold, silver, copper, zinc and lead were all dug out of the rock here. Unfortunately, the process released cadmium into the river, which, when taken up by the rice that was grown in the river, caused the terrible itai-itai disease - meaning "It hurts! It hurts". Cadm...
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http://www.miniatur-wunderland.com/
Not sure if Hamburg is on your proposed itinerary, but this is also impressive :)
signol
Early start from London though. Join the night train in Amsterdam, or elsewhere en route (eg Rotterdam)...
signol