Thanks to this thread on airliners.net I found some interesting model railway related "sights" in Prague. One suggested accommodation was the Ibis Hotel Mala Strana. Close by is Railroad Kingdom. My Googling also found the Vytopna Restaurant in Prague where the drinks are served by model trains.
I've always loved to travel. My first memory is of sitting in a an aircraft, aged 18 months or so. Yet I never believed that I could travel overseas. To me, it seemed like something you did when you retired, or if you were rich. That all changed when I met B. She had not only travelled overseas, she was from overseas . B was born in Malaysia and arrived in Australia, with her family, in 1988. She still had relatives and friends in Malaysia and Singapore and she, along with the remainder of her family, planned to return for a visit during the Australian summer of 1995. At the time I was staying in B's mother's house while we were studying at university. After B's father passed away the year before I was the nominal "man" of the house and its high maintenance garden; her brother Michael was studying up in Queensland. B and I were quite inseparable and her mother kindly offered to pay for me to join them on their vacation. So it was that I obtained my very firs...
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http://www.miniatur-wunderland.com/
Not sure if Hamburg is on your proposed itinerary, but this is also impressive :)
signol
Early start from London though. Join the night train in Amsterdam, or elsewhere en route (eg Rotterdam)...
signol